| San Francisco 49ers | @ | Minnesota Vikings | |
| Standing | 17 | : | 23 |
| Box score | 0 / 7 / 0 / 10 | | | 3 / 10 / 7 / 3 |
| Purdy | Darnold | |||
| | | 28 - 36 / 319 yds / 1 TD / 1 INT / 101,3 Rating | | | 17 - 26 / 268 yds / 2 TD / 1 INT/ 109,1 Rating |
| Mason | Chandler | |||
| | | 20 Att / 100 yds / 1 TD | | | 10 Att, 82 yds, 0 TD |
| Samuel | Jefferson | |||
| | | 8 - 10 Rec / 110 yds / 0 TD | | | 4 - 7 Rec, 133 yds / 1 TD |
| Moody | Reichard | |||
| | | 1-1 FG / 2-2 PAT / 31 yds long | | | 3-3 FG / 2-2 PAT / 39 yds long |
| Warner | Pace jr. | |||
| | | 7 Tac / 2 Ass / 2 FF / 1 Sac | | | 6 Tac / 2 Ass / 0 FF / 0 Sac |
| Niners | Vikings | |||
| Time of possession | | | 34 : 48 | | | 25 : 12 |
| Total Yards/Plays/Drives | | | 399 / 67 / 10 | | | 403 / 54 / 11 |
| Passing/Att/1stdowns | | | 297 yds / 28-36 / 17 | | | 257 yds / 17-26 / 9 |
| Rushing/Att/1stdowns | | | 102 yds / 25 / 5 | | | 146 yds / 1724 / 8 |
| First Downs/by penalty | | | 24 / 2 | | | 17 / 0 |
| Third Downs | | | 2 – 10 / 20 % | | | 7 – 12 / 58 % |
| Fourth Downs | | | 1 - 3 | | | 0 - 0 |
| Red Zone/TD | | | 2 – 4 / 50 % | | | 1 - 3 / 33 % |
| Ave Yds per play | | | 6,0 | | | 7,5 |
| Ave Yds per Rush/Pass | | | 4,1 / 7,1 | | | 6,1 / 8,6 |
| Penalties-Yards | | | 4 – 30 | | | 7 - 53 |
| Sacked- Yards Lost | | | 6 - 22 | | | 4 - 11 |
| Fumbles/Lost | | | 3 / 1 | | | 3 / 1 |
| Interceptions Thrown | | | 1 | | | 1 |
| Punts/In20/TB | | | 2 / 2 / 0 | | | 3 / 1 / 1 |
| Ave Punt/Long | | | 49,5 / 58,0 | | | 50,3 / 56,0 |