| Tampa Bay Buccaneers | @ | San Francisco 49ers | |
| Standing | 14 | : | 27 |
| Box score | 0 / 7 / 0 / 7 | | | 7 / 6 / 14 / 0 |
| Mayfield | Purdy | |||
| | | 29 - 45 / 246 yds / 1 TD / 1 INT / 76,7 Rating | | | 21 - 25 / 333 yds / 3 TD / 0 INT/ 158,3 Rating |
| White | McCaffrey | |||
| | | 9 Att / 30 yds / 1 TD | | | 21 Att, 78 yds, 0 TD |
| Otton | Aiyuk | |||
| | | 4 Rec, 5 Tgt / 49 yds / 0 TD | | | 5 Rec, 6 Tgt / 156 yds / 1 TD |
| McLaughlin | Moody | |||
| | | 0-0 FG / 2-2 PAT / - | | | 2-2 FG / 3-3 PAT / 37y long |
| Winfield Jr. | Warner | |||
| | | 9 Tac / 7 Ass / 0 FF / 0 Sac | | | 10 Tac / 2 Ass / 1 FF / 0,5 Sac |
| Buccaneers | Niners | |||
| Time of possession | | | 29 : 09 | | | 30 : 51 |
| Total Yards/Plays/Drives | | | 287 / 67 / 10 | | | 420 / 59 / 10 |
| Passing/Att/1stdowns | | | 221 yds / 29-45 / 14 | | | 305 yds / 21-25 / 14 |
| Rushing/Att/1stdowns | | | 66 yds / 18 / 7 | | | 115 yds / 30 / 7 |
| First Downs/by penalty | | | 22 / 1 | | | 22 / 1 |
| Third Downs | | | 7 – 14 / 50 % | | | 4 – 10 / 40 % |
| Fourth Downs | | | 1 – 3 | | | 0 – 1 |
| Red Zone/TD | | | 2 – 4 / 50 % | | | 2 – 4 / 50 % |
| Ave Yds per play | | | 4,3 | | | 7,1 |
| Ave Yds per Rush/Pass | | | 3,7 / 4,5 | | | 3,8 / 10,5 |
| Penalties-Yards | | | 3– 19 | | | 7 - 66 |
| Sacked- Yards Lost | | | 4 - 25 | | | 4 - 28 |
| Fumbles / Lost | | | 2 / 1 | | | 0 / 0 |
| Interceptions Thrown | | | 1 | | | 0 |
| Punts/In20/TB | | | 3 / 1 / 0 | | | 3 / 0 / 0 |
| Ave Punt/Long | | | 48,0 / 56,0 | | | 51,0 / 60,0 |